Cooperativity in Binding Processes: New Insights from Phenomenological Modeling.

Cooperative binding is one of the most interesting and not fully understood phenomena involved in control and regulation of biological processes. Here we analyze the simplest phenomenological model that can account for cooperativity (i.e. ligand binding to a macromolecule with two binding sites) by...

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Bibliographic Details
Main Authors: Diego I Cattoni, Osvaldo Chara, Sergio B Kaufman, F Luis González Flecha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4696654?pdf=render