Low VDAC1 Expression Is Associated with an Aggressive Phenotype and Reduced Overall Patient Survival in Cholangiocellular Carcinoma

Cancer cells frequently exhibit dysfunctional oxidative phosphorylation (OXPHOS) and a concomitant increase in glycolytic flux. We investigated the expression of OXPHOS complex subunits and mitochondrial mass in 34 human cholangiocellular carcinomas (CCCs) and adjacent normal tissue by using tissue...

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Bibliographic Details
Main Authors: René Günther Feichtinger, Daniel Neureiter, Ralf Kemmerling, Johannes Adalbert Mayr, Tobias Kiesslich, Barbara Kofler
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/6/539