Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells

Complex spike burst discharges of hippocampal neurons are proposed to be important for plasticity. Here, the authors report that in CA3 pyramidal neurons complex bursts generated by intrinsic mechanisms, can represent heterogeneous input-output functions and are regulated by HCN and Kv2 channels.

Bibliographic Details
Main Authors: Snezana Raus Balind, Ádám Magó, Mahboobeh Ahmadi, Noémi Kis, Zsófia Varga-Németh, Andrea Lőrincz, Judit K. Makara
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09767-w