Functional variation of SHP-2 promoter is associated with preterm birth and delayed myelination and motor development in preterm infants

Functional variation of SHP-2 promoter is associated with preterm birth and delayed myelination and motor development in preterm infants

Abstract Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP-2) is a cytoplasmic tyrosine phosphatase that is highly expressed in hematopoietic cells and in the CNS and exerts opposite effects on signal transduction by exerting a neuroprotective or proapoptotic effect. Several mutat...

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Bibliographic Details
Main Authors: So-Yeon Shim, Hye Jin Jeong, Hyo Jin Park, Eun Young Kwon, Bo Min Kim, Yang Ji Choi, Youn-Hee Choi, Su Jin Cho, Ji Ha Choi, Eun Ae Park
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06401-x

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https://doi.org/10.1038/s41598-017-06401-x

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