IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages

IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages

Syphilis is a multi-stage, sexually transmitted disease caused by the spirochete Treponema pallidum (Tp). Considered broadly, syphilis can be conceptualized as a dualistic process in which spirochete-driven inflammation, the cause of clinical manifestations, coexists to varying extents with bacteria...

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Bibliographic Details
Main Authors: Kelly L. Hawley, Adriana R. Cruz, Sarah J. Benjamin, Carson J. La Vake, Jorge L. Cervantes, Morgan LeDoyt, Lady G. Ramirez, Daniza Mandich, Mary Fiel-Gan, Melissa J. Caimano, Justin D. Radolf, Juan C. Salazar
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
Treponema pallidum
human
macrophage
Fcγ receptor
phagocytosis
phagosomal signaling
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01227/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01227/full

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