Determining Genetic Causal Variants Through Multivariate Regression Using Mixture Model Penalty

With the availability of high-throughput sequencing data, identification of genetic causal variants accurately requires the efficient incorporation of function annotation data into the optimization routine. This motivates the need for development of novel methods for genome wide association studies...

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Bibliographic Details
Main Authors: V. S. Sundar, Chun-Chieh Fan, Dominic Holland, Anders M. Dale
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2018.00077/full