FGF10 Enhances Peripheral Nerve Regeneration via the Preactivation of the PI3K/Akt Signaling-Mediated Antioxidant Response

FGF10 Enhances Peripheral Nerve Regeneration via the Preactivation of the PI3K/Akt Signaling-Mediated Antioxidant Response

The process of axonal regeneration after peripheral nerve injury (PNI) is slow and mostly incomplete. Previous studies have investigated the neuroprotective effects of fibroblast growth factor 10 (FGF10) against spinal cord injury and cerebral ischemia brain injury. However, the role of FGF10 in per...

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Bibliographic Details
Main Authors: Lvpeng Dong, Rui Li, Duohui Li, Beini Wang, Yingfeng Lu, Peifeng Li, Fangzheng Yu, Yonglong Jin, Xiao Ni, Yanqing Wu, Shengnan Yang, Guanxi Lv, Xiaokun Li, Jian Xiao, Jian Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
Subjects:
fibroblast growth factor 10
axonal regeneration
peripheral nerve injury
oxidative stress
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01224/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01224/full

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