Feasibility of Targeting Traf2-and-Nck-Interacting Kinase in Synovial Sarcoma

Feasibility of Targeting Traf2-and-Nck-Interacting Kinase in Synovial Sarcoma

Background: The treatment of patients with metastatic synovial sarcoma is still challenging, and the development of new molecular therapeutics is desirable. Dysregulation of Wnt signaling has been implicated in synovial sarcoma. Traf2-and-Nck-interacting kinase (TNIK) is an essential transcriptional...

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Bibliographic Details
Main Authors: Tetsuya Sekita, Tesshi Yamada, Eisuke Kobayashi, Akihiko Yoshida, Toru Hirozane, Akira Kawai, Yuko Uno, Hideki Moriyama, Masaaki Sawa, Yuichi Nagakawa, Akihiko Tsuchida, Morio Matsumoto, Masaya Nakamura, Robert Nakayama, Mari Masuda
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
Wnt signaling
synovial sarcoma
TNIK
NCB-0846
MYC
Online Access:https://www.mdpi.com/2072-6694/12/5/1258

Internet

https://www.mdpi.com/2072-6694/12/5/1258

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