The expression of BAFF, APRIL and TWEAK is altered in eczema skin but not in the circulation of atopic and seborrheic eczema patients.

The expression of BAFF, APRIL and TWEAK is altered in eczema skin but not in the circulation of atopic and seborrheic eczema patients.

The TNF family cytokines BAFF (B-cell activating factor of the TNF family) and APRIL (a proliferation-inducing ligand) are crucial survival factors for B-cell development and activation. B-cell directed treatments have been shown to improve atopic eczema (AE), suggesting the involvement of these cyt...

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Bibliographic Details
Main Authors: Yunying Chen, Sara Lind Enoksson, Catharina Johansson, Maria A Karlsson, Lena Lundeberg, Gunnar Nilsson, Annika Scheynius, Mikael C I Karlsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3135616?pdf=render

Internet

http://europepmc.org/articles/PMC3135616?pdf=render

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