Favorable outcome of patients with lung adenocarcinoma harboring POLE mutations and expressing high PD-L1

Favorable outcome of patients with lung adenocarcinoma harboring POLE mutations and expressing high PD-L1

Abstract Mutations in polymerase ε (POLE) confer favorable prognosis and outcomes in various cancer types, but their role in non-small cell lung cancer (NSCLC) is unknown. Utilizing the data of 513 patients with adenocarcinoma (LUAD) and 497 patients with squamous cell carcinoma (LUSC) from The Canc...

Full description

Bibliographic Details
Main Authors: Liang Liu, Jimmy Ruiz, Stacey S. O’Neill, Stefan C. Grant, W. Jeffrey Petty, Meng Yang, Kexin Chen, Umit Topaloglu, Boris Pasche, Wei Zhang
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Molecular Cancer
Subjects:
POLE mutation
PD-L1 expression
Lung cancer adenocarcinoma
Lung cancer squamous cell carcinoma
Overall survival
Non-small cell lung cancer
Online Access:http://link.springer.com/article/10.1186/s12943-018-0832-y

Internet

http://link.springer.com/article/10.1186/s12943-018-0832-y

Similar Items