Extreme Drug Tolerance of Mycobacterium abscessus “Persisters”

Persistence of infection despite extensive chemotherapy with antibiotics displaying low MICs is a hallmark of lung disease caused by Mycobacterium abscessus (Mab). Thus, the classical MIC assay is a poor predictor of clinical outcome. Discovery of more efficacious antibiotics requires more predictiv...

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Bibliographic Details
Main Authors: Yee-Kuen Yam, Nadine Alvarez, Mei-Lin Go, Thomas Dick
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
NTM
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00359/full