Immuno-metabolic impact of the multiple sclerosis patients’ sera on endothelial cells of the blood-brain barrier

Immuno-metabolic impact of the multiple sclerosis patients’ sera on endothelial cells of the blood-brain barrier

Abstract Background Multiple sclerosis (MS) is an autoimmune disease which results from the invasion of the brain by activated immune cells across the endothelial cells (ECs) of the blood-brain barrier (BBB), due to loss of immune self-tolerance. Many reports define the metabolic profile of immune c...

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Bibliographic Details
Main Authors: M. H. Sheikh, S. M. Henson, R. A. Loiola, S. Mercurio, A. Colamatteo, G. T. Maniscalco, V. De Rosa, S. McArthur, E. Solito
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Neuroinflammation
Subjects:
Metabolism
Multiple sclerosis
Blood-brain barrier
Tight junction
Cytoskeleton
Online Access:http://link.springer.com/article/10.1186/s12974-020-01810-8

Internet

http://link.springer.com/article/10.1186/s12974-020-01810-8

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