Uncovering the Pharmacological Mechanism of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Against Lung Cancer Based on Network Pharmacology and Experimental Evaluation

Uncovering the Pharmacological Mechanism of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Against Lung Cancer Based on Network Pharmacology and Experimental Evaluation

Background: 2-Dodecyl-6-Methoxycyclohexa-2, 5-Diene-1,4-Dione (DMDD) was purified from the roots of Averrhoa carambola L. Previous research demonstrated that DMDD is a small molecular compound with significant therapeutic potential for tumors. However, the potential targets and pharmacological mecha...

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Bibliographic Details
Main Authors: Lihui Wang, Xin Yang, Qiong Song, Jiejun Fu, Wenchu Wang, Kechen Du, Shuai Chen, Jinjin Cao, Renbin Huang, Chunlin Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
DMDD
lung cancer
network pharmacology
cell cycle arrest
TCGA
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.617555/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.617555/full

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