Administration of Intravenous Iron Formulations Induces Complement Activation in-vivo

Administration of Intravenous Iron Formulations Induces Complement Activation in-vivo

Background: Intravenous (IV) iron is widely used to treat anemia in chronic kidney disease patients. Previously, iron formulations were shown to induce immune activation in-vitro. The current study aimed to investigate the effect of IV iron on complement activation in-vivo, and whether this subseque...

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Bibliographic Details
Main Authors: Bernardo Faria, Mariana Gaya da Costa, Felix Poppelaars, Casper F. M. Franssen, Manuel Pestana, Stefan P. Berger, Mohamed R. Daha, Carlo A. J. M. Gaillard, Marc A. Seelen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
kidney
complement
hemodialysis
iron
anemia and kidney disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01885/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01885/full

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