Estrogen prevent atherosclerosis by attenuating endothelial cell pyroptosis via activation of estrogen receptor α-mediated autophagy

Estrogen prevent atherosclerosis by attenuating endothelial cell pyroptosis via activation of estrogen receptor α-mediated autophagy

Introduction: Excessive inflammation and the pyroptosis of vascular endothelial cells caused by estrogen deficiency is one cause of atherosclerosis in post-menopausal women. The autophagy is highly regulated by estrogen, however whether estrogen can reduce vascular endothelial cell pyroptosis throug...

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Bibliographic Details
Main Authors: Qinghai Meng, Yu Li, Tingting Ji, Ying Chao, Jun Li, Yu Fu, Suyun Wang, Qi Chen, Wen Chen, Fuhua Huang, Youran Wang, Qichun Zhang, Xiaoliang Wang, Huimin Bian
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Journal of Advanced Research
Subjects:
Menopause
Estrogen
Atherosclerosis
Autophagy
Inflammation
Pyroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123220301983

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http://www.sciencedirect.com/science/article/pii/S2090123220301983

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