Autophagic activation of IRF‐1 aggravates hepatic ischemia–reperfusion injury via JNK signaling

Abstract Increasing evidence has accrued indicating that autophagy is associated with hepatic ischemia–reperfusion injury (IRI). This report demonstrates that interferon regulatory factor‐1 (IRF‐1) was upregulated in response to hepatic IRI and was associated with autophagic activation. As a result...

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Bibliographic Details
Main Authors: Shipeng Li, Jindan He, Hongwei Xu, Jiaxing Yang, Yutian Luo, Wenyue Song, Bingbing Qiao, Haiming Zhang
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:MedComm
Subjects:
JNK
Online Access:https://doi.org/10.1002/mco2.58