The RECK tumor-suppressor protein binds and stabilizes ADAMTS10

The RECK tumor-suppressor protein binds and stabilizes ADAMTS10

The tumor suppressor protein RECK has been implicated in the regulation of matrix metalloproteinases (MMPs), NOTCH-signaling and WNT7-signaling. It remains unclear, however, how broad the spectrum of RECK targets extends. To find novel RECK binding partners, we took the unbiased approach of yeast tw...

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Bibliographic Details
Main Authors: Tomoko Matsuzaki, Hitoshi Kitayama, Akira Omura, Emi Nishimoto, David B. Alexander, Makoto Noda
Format: Article
Language:English
Published: The Company of Biologists 2018-10-01
Series:Biology Open
Subjects:
RECK
ADAMTS10
Tumor suppressor
Fibronectin
MT1-MMP
Yeast two-hybrid assay
Online Access:http://bio.biologists.org/content/7/10/bio033985

Internet

http://bio.biologists.org/content/7/10/bio033985

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