An Optically Induced Dielectrophoresis (ODEP)-Based Microfluidic System for the Isolation of High-Purity CD45<sup>neg</sup>/EpCAM<sup>neg</sup> Cells from the Blood Samples of Cancer Patients—Demonstration and Initial Exploration of the Clinical Significance of These Cells

An Optically Induced Dielectrophoresis (ODEP)-Based Microfluidic System for the Isolation of High-Purity CD45<sup>neg</sup>/EpCAM<sup>neg</sup> Cells from the Blood Samples of Cancer Patients—Demonstration and Initial Exploration of the Clinical Significance of These Cells

Circulating tumour cells (CTCs) in blood circulation play an important role in cancer metastasis. CTCs are generally defined as the cells in circulating blood expressing the surface antigen EpCAM (epithelial cell adhesion molecule). Nevertheless, CTCs with a highly metastatic nature might undergo an...

Full description

Bibliographic Details
Main Authors: Chia-Jung Liao, Chia-Hsun Hsieh, Tzu-Keng Chiu, Yu-Xian Zhu, Hung-Ming Wang, Feng-Chun Hung, Wen-Pin Chou, Min-Hsien Wu
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Micromachines
Subjects:
microfluidic systems
optically induced dielectrophoresis (ODEP)
cell isolation
circulating tumour cells (CTCs)
cancer metastasis
Online Access:https://www.mdpi.com/2072-666X/9/11/563

Internet

https://www.mdpi.com/2072-666X/9/11/563

Similar Items