The Importance of Lipoprotein Lipase Regulation in Atherosclerosis

Lipoprotein lipase (LPL) plays a major role in the lipid homeostasis mainly by mediating the intravascular lipolysis of triglyceride rich lipoproteins. Impaired LPL activity leads to the accumulation of chylomicrons and very low-density lipoproteins (VLDL) in plasma, resulting in hypertriglyceridemi...

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Bibliographic Details
Main Authors: Anni Kumari, Kristian K. Kristensen, Michael Ploug, Anne-Marie Lund Winther
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/7/782