Inhibition of miR-153 ameliorates ischemia/reperfusion-induced cardiomyocytes apoptosis by regulating Nrf2/HO-1 signaling in rats

Inhibition of miR-153 ameliorates ischemia/reperfusion-induced cardiomyocytes apoptosis by regulating Nrf2/HO-1 signaling in rats

Abstract Background Previous in vitro studies demonstrated that suppression of microRNAs might protect cardiomyocytes and neurons against oxygen–glucose deprivation and reoxygenation (OGD/R)-induced cell apoptosis. However, whether the protective effect of miR-153-inhibition on cardiomyocytes can be...

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Bibliographic Details
Main Authors: Wei Hou, Xianting Zhu, Juan Liu, Jiaguo Map
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BioMedical Engineering OnLine
Subjects:
Ischemia–reperfusion
Rat
MiR-153
Nrf2
Adenoviral delivery
Online Access:http://link.springer.com/article/10.1186/s12938-020-0759-6

Internet

http://link.springer.com/article/10.1186/s12938-020-0759-6

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