Lymphatic endothelial cells – key players in regulation of tolerance and immunity

Lymphatic endothelial cells – key players in regulation of tolerance and immunity

The lymphatic vasculature provides routes for dendritic cell and lymphocyte migration into and out of lymph nodes. Lymphatic endothelial cells (LEC) control these processes by expression of CCL21, sphingosine-1-phosphate and adhesion molecules. LEC express MHC-I and MHC-II, but not costimulatory mol...

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Bibliographic Details
Main Authors: Eric eTewalt, Jarish eCohen, Sherin eRouhani, Victor eEngelhard
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Immunology
Subjects:
Antigen Presentation
Lymph Node
lymphatics
tolerance mechanisms
lymph node stromal cells
lymphatic endothelial cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00305/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00305/full

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