CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.

CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.

Despite chronic inflammation, psoriatic lesions hardly ever progress to skin cancer. Aberrant function of the CCHCR1 gene (Coiled-Coil alpha-Helical Rod protein 1, HCR) within the PSORS1 locus may contribute to the onset of psoriasis. As CCHCR1 is expressed in certain cancers and regulates keratinoc...

Full description

Bibliographic Details
Main Authors: Sari Suomela, Outi Elomaa, Tiina Skoog, Risto Ala-aho, Leila Jeskanen, Jenita Pärssinen, Leena Latonen, Reidar Grénman, Juha Kere, Veli-Matti Kähäri, Ulpu Saarialho-Kere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19551138/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19551138/pdf/?tool=EBI

Similar Items