CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.

CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.

Despite chronic inflammation, psoriatic lesions hardly ever progress to skin cancer. Aberrant function of the CCHCR1 gene (Coiled-Coil alpha-Helical Rod protein 1, HCR) within the PSORS1 locus may contribute to the onset of psoriasis. As CCHCR1 is expressed in certain cancers and regulates keratinoc...

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Main Authors: Sari Suomela, Outi Elomaa, Tiina Skoog, Risto Ala-aho, Leila Jeskanen, Jenita Pärssinen, Leena Latonen, Reidar Grénman, Juha Kere, Veli-Matti Kähäri, Ulpu Saarialho-Kere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19551138/pdf/?tool=EBI

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