Candida albicans Pma1p Contributes to Growth, pH Homeostasis, and Hyphal Formation

Candida albicans Pma1p Contributes to Growth, pH Homeostasis, and Hyphal Formation

Candida albicans occupies diverse ecological niches within the host and must tolerate a wide range of environmental pH. The plasma membrane H+-ATPase Pma1p is the major regulator of cytosolic pH in fungi. Pma1p extrudes protons from the cytosol to maintain neutral-to-alkaline pH and is a potential d...

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Bibliographic Details
Main Authors: Hallie S. Rane, Summer R. Hayek, Jillian E. Frye, Esteban L. Abeyta, Stella M. Bernardo, Karlett J. Parra, Samuel A. Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Microbiology
Subjects:
Candida albicans
cytosolic pH
filamentation
glucose metabolism
pH homeostasis
plasma membrane H+ ATPase
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01012/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01012/full

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