Wnt Pathway Activation in Long Term Remnant Rat Model

Progression of chronic kidney disease (CKD) is characterized by deposition of extracellular matrix. This is an irreversible process that leads to tubulointerstitial fibrosis and finally loss of kidney function. Wnt/β-catenin pathway was reported to be aberrantly activated in the progressive damage a...

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Bibliographic Details
Main Authors: E. Banon-Maneus, J. Rovira, M. J. Ramirez-Bajo, D. Moya-Rull, N. Hierro-Garcia, S. Takenaka, F. Diekmann, O. Eickelberg, M. Königshoff, J. M. Campistol
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/324713