The Role of Tumor Necrosis Factor in Manipulating the Immunological Response of Tumor Microenvironment

The Role of Tumor Necrosis Factor in Manipulating the Immunological Response of Tumor Microenvironment

The tumor microenvironment (TME) is an intricate system within solid neoplasms. In this review, we aim to provide an updated insight into the TME with a focus on the effects of tumor necrosis factor-α (TNF-α) on its various components and the use of TNF-α to improve the efficiency of drug delivery....

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Bibliographic Details
Main Authors: Dipranjan Laha, Robert Grant, Prachi Mishra, Naris Nilubol
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
tumor necrosis factor-α
transforming growth factor beta
extracellular matrix
interstitial fluid pressure
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.656908/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.656908/full

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