Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy

The CADUCEUS trial of cardiosphere-derived cells (CDCs) has shown that it may be possible to regenerate injured heart muscle previously thought to be permanently scarred. The mechanisms of benefit are known to be indirect, but the mediators have yet to be identified. Here we pinpoint exosomes secret...

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Bibliographic Details
Main Authors: Ahmed Gamal-Eldin Ibrahim, Ke Cheng, Eduardo Marbán
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114001131