Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis

To clarify the molecular mechanisms underlying multiple sclerosis (MS)-promoting autoimmune process, we have investigated a comprehensive gene expression profile of T cell and non-T cell fractions of peripheral blood mononuclear cells (PBMC) isolated from 72 MS patients and 22 age- and sex-matched h...

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Bibliographic Details
Main Authors: Jun-ichi Satoh, Megumi Nakanishi, Fumiko Koike, Sachiko Miyake, Toshiyuki Yamamoto, Mitsuru Kawai, Seiji Kikuchi, Kyouichi Nomura, Kazumasa Yokoyama, Kohei Ota, Takashi Kanda, Toshiyuki Fukazawa, Takashi Yamamura
Format: Article
Language:English
Published: Elsevier 2005-04-01
Series:Neurobiology of Disease
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Online Access:http://www.sciencedirect.com/science/article/pii/S096999610400244X