Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice

Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice

Pulmonary fibrosis is a known sequela of severe or persistent lung damage. Existing clinical, imaging and autopsy studies have shown that the lungs exhibit a pathological pulmonary fibrosis phenotype after infection with coronaviruses, including severe acute respiratory syndrome coronavirus 2 (SARS-...

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Bibliographic Details
Main Authors: Xiaohe Li, Rui Liu, Yunyao Cui, Jingjing Liang, Zhun Bi, Shimeng Li, Yang Miao, Liang Zhang, Xiaoping Li, Honggang Zhou, Cheng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
remdesivir (RDV)
COVID-19
pulmonary fibrosis
bleomycin
TGF-β1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.692346/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.692346/full

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