Morphological Abnormalities and Gene Expression Changes Caused by High Incubation Temperatures in Zebrafish Xenografts with Human Cancer Cells

Published studies show that most of the human cancer xenograft studies in zebrafish embryos have used incubation temperatures in the range of 32–34 °C for 3–6 days post-injection, trying to find a compromise temperature between the zebrafish embryos (28 °C) and the human injected cells (37 °C). Whil...

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Bibliographic Details
Main Authors: Pablo Cabezas-Sainz, Carlos Coppel, Alba Pensado-López, Pedro Fernandez, Laura Muinelo-Romay, Rafael López-López, Juan A. Rubiolo, Laura Sánchez
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/1/113