HER2, chromosome 17 polysomy and DNA ploidy status in breast cancer; a translational study

HER2, chromosome 17 polysomy and DNA ploidy status in breast cancer; a translational study

Abstract Breast cancer treatment depends on human epidermal growth factor receptor-2 (HER2) status, which is often determined using dual probe fluorescence in situ hybridisation (FISH). Hereby, also loss and gain of the centromere of chromosome 17 (CEP17) can be observed (HER2 is located on chromoso...

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Bibliographic Details
Main Authors: Altuna Halilovic, Dagmar I. Verweij, Annet Simons, Marian J. P. L. Stevens-Kroef, Susan Vermeulen, Janet Elsink, Bastiaan B. J. Tops, Irene Otte-Höller, Jeroen A. W. M. van der Laak, Carlijn van de Water, Oliver B. A. Boelens, Margrethe S. Schlooz-Vries, Jeroen R. Dijkstra, Iris D. Nagtegaal, Jolien Tol, Patricia H. J. van Cleef, Paul N. Span, Peter Bult
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-48212-2

Internet

https://doi.org/10.1038/s41598-019-48212-2

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