Uncovering the dual role of RHAMM as an HA receptor and a regulator of CD44 expression in RHAMM-expressing mesenchymal progenitor cells

Uncovering the dual role of RHAMM as an HA receptor and a regulator of CD44 expression in RHAMM-expressing mesenchymal progenitor cells

The interaction of hyaluronan (HA) with mesenchymal progenitor cells impacts trafficking and fate after tissue colonization during wound repair and these events contribute to diseases such as cancer. How this interaction occurs is poorly understood. Using 10T½ cells as a mesenchymal progenitor model...

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Bibliographic Details
Main Authors: Mandana eVeiseh, Sean eLeith, Cornelia eTolg, Bahram eBahrami, Lisa eCollis, Sara eHamilton, James eMcCarthy, Mina J Bissell, Eva eTurley
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
progenitor
CD44
hyaluronan
RHAMM
HMMR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00063/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00063/full

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