Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis
Bone remodeling involves a balance between bone resorption and formation. The mechanisms underlying bone remodeling are not well understood. DEF6 is recently identified as a novel loci associated with bone mineral density. However, it is unclear how Def6 impacts bone remodeling. We identify Def6 as...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-12-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/59659 |