Nucleolar localization of RNA binding proteins induced by actinomycin D and heat shock in Trypanosoma cruzi.

In this work we show that under Actinomycin D (ActD) treatment, several RNA Binding Proteins (RBPs) involved in mRNA metabolism are relocalized into the nucleolus in Trypanosoma cruzi as a specific stress response. ATP depletion as well as kinase inhibition markedly reduced the nucleolar localizatio...

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Bibliographic Details
Main Authors: Ezequiel Názer, Ramiro E Verdún, Daniel O Sánchez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3101214?pdf=render