Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast

Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast

Most eukaryotic mRNAs accommodate alternative sites of poly(A) addition in the 3’ untranslated region in order to regulate mRNA function. Here, we present a systematic analysis of 3’ end formation factors, which revealed 3’UTR lengthening in response to a loss of the core machinery, whereas a loss o...

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Bibliographic Details
Main Authors: Rachael Emily Turner, Paul F Harrison, Angavai Swaminathan, Calvin A Kraupner-Taylor, Belinda J Goldie, Michael See, Amanda L Peterson, Ralf B Schittenhelm, David R Powell, Darren J Creek, Bernhard Dichtl, Traude H Beilharz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
alternative polyadenylation
transcription elongation
cleavage
polyadenylation
cordycepin
mycophenolic acid
Online Access:https://elifesciences.org/articles/65331

Internet

https://elifesciences.org/articles/65331

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