Discovery of high-affinity protein binding ligands--backwards.

Discovery of high-affinity protein binding ligands--backwards.

BACKGROUND: There is a pressing need for high-affinity protein binding ligands for all proteins in the human and other proteomes. Numerous groups are working to develop protein binding ligands but most approaches develop ligands using the same strategy in which a large library of structured ligands...

Full description

Bibliographic Details
Main Authors: Chris W Diehnelt, Miti Shah, Nidhi Gupta, Paul E Belcher, Matthew P Greving, Phillip Stafford, Stephen Albert Johnston
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2873402?pdf=render

Internet

http://europepmc.org/articles/PMC2873402?pdf=render

Similar Items