Methylation of DACT2 promotes breast cancer development by activating Wnt signaling

Abstract Breast cancer is the most common malignant tumor in women worldwide. To explore the role of DACT2 in breast cancer, 5 cell lines and 153 cases of primary cancer were studied. The expression of DACT2 was detected in BT474, MDA-MB-231 and BT549 cells, while no expression was found in MDA-MB-4...

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Bibliographic Details
Main Authors: Jingyi Li, Meiying Zhang, Tao He, Hongxia Li, Tingting Cao, Lili Zheng, Mingzhou Guo
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03647-3