Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs

Abstract PIWI proteins, a subfamily of PAZ/PIWI Domain family RNA-binding proteins, are best known for their function in silencing transposons and germline development by partnering with small noncoding RNAs called PIWI-interacting RNAs (piRNAs). However, recent studies have revealed multifaceted ro...

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Bibliographic Details
Main Authors: Chen Wang, Haifan Lin
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-020-02221-x