Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality

Molecular and anatomical functions of mammalian Dip2 family members (Dip2A, Dip2B and Dip2C) during organogenesis are largely unknown. Here, we explored the indispensable role of Dip2B in mouse lung development. Using a LacZ reporter, we explored Dip2B expression during embryogenesis. This study sho...

Full description

Bibliographic Details
Main Authors: Rajiv Kumar Sah, Jun Ma, Fatoumata Binta Bah, Zhenkai Xing, Salah Adlat, Zin Ma Oo, Yajun Wang, Noor Bahadar, Ameer Ali Bohio, Farooq Hayel Nagi, Xuechao Feng, Luqing Zhang, Yaowu Zheng
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
Dip2b
LacZ expression
growth restriction
fetal lung development
prenatal lethality
RNA sequencing
Online Access:https://www.mdpi.com/1422-0067/21/21/8223

Internet

https://www.mdpi.com/1422-0067/21/21/8223

Similar Items