Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth

Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth

Abstract Background It is unclear whether plant-derived extracellular vesicles (EVs) can mediate interspecies communication with mammalian cells. Tumor-associated macrophages (TAMs) display a continuum of different polarization states between tumoricidal M1 phenotype and tumor-supportive M2 phenotyp...

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Bibliographic Details
Main Authors: Meng Cao, Huaijiang Yan, Xuan Han, Ling Weng, Qin Wei, Xiaoyan Sun, Wuguang Lu, Qingyun Wei, Juan Ye, Xueting Cai, Chunping Hu, Xiaoyang Yin, Peng Cao
Format: Article
Language:English
Published: BMJ Publishing Group 2019-11-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Extracellular vesicles (EVs)
Ginseng-derived nanoparticles
Tumor-associated macrophages (TAM)
Macrophage polarization
Melanoma
Online Access:http://link.springer.com/article/10.1186/s40425-019-0817-4

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http://link.springer.com/article/10.1186/s40425-019-0817-4

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