Synthesis and evaluation of novel naphthol diazenyl scaffold based Schiff bases as potential antimicrobial and cytotoxic agents against human colorectal carcinoma cell line (HT-29)

Synthesis and evaluation of novel naphthol diazenyl scaffold based Schiff bases as potential antimicrobial and cytotoxic agents against human colorectal carcinoma cell line (HT-29)

Abstract Background In search of new antimicrobial and cytotoxic agents, a series of new naphthol diazenyl scaffold based Schiff bases (NS1–NS23) was efficiently synthesized by condensation of 2-hydroxy naphthaldehyde azo dyes with various substituted aromatic/heteroaromatic/aliphatic amines. Method...

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Bibliographic Details
Main Authors: Harmeet Kaur, Jasbir Singh, Balasubramanian Narasimhan
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Chemistry
Subjects:
Schiff base
Antimicrobial
Diazenyl
Apoptosis
Cell cycle
Online Access:http://link.springer.com/article/10.1186/s13065-019-0558-y

Internet

http://link.springer.com/article/10.1186/s13065-019-0558-y

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