Exploration of the Combination of PLK1 Inhibition with Immunotherapy in Cancer Treatment

Background. PLK1 overexpression is oncogenic and is associated with poor prognosis in various cancers. However, the current PLK1 inhibitors have achieved limited clinical successes. On the other hand, although immunotherapies are demonstrating efficacy in treating many refractory cancers, a substant...

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Bibliographic Details
Main Authors: Mengyuan Li, Zhixian Liu, Xiaosheng Wang
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2018/3979527