Traumatic brain injury induces region-specific glutamate metabolism changes as measured by multiple mass spectrometry methods

Traumatic brain injury induces region-specific glutamate metabolism changes as measured by multiple mass spectrometry methods

Summary: The release of excess glutamate following traumatic brain injury (TBI) results in glutamate excitotoxicity and metabolic energy failure. Endogenous mechanisms for reducing glutamate concentration in the brain parenchyma following TBI are poorly understood. Using multiple mass spectrometry a...

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Bibliographic Details
Main Authors: James L. Sowers, Mark L. Sowers, Alexander S. Shavkunov, Bridget E. Hawkins, Ping Wu, Douglas S. DeWitt, Donald S. Prough, Kangling Zhang
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:iScience
Subjects:
Molecular physiology
Neuroscience
Metabolomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221010762

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http://www.sciencedirect.com/science/article/pii/S2589004221010762

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