Growth Arrest-Specific Transcript 5 (GAS5) Exerts Important Roles on the Treatment of BM45 Cells of Liver Cirrhosis

Growth Arrest-Specific Transcript 5 (GAS5) Exerts Important Roles on the Treatment of BM45 Cells of Liver Cirrhosis

Bone marrow (BM)-derived CD45 (BM45) cells were demonstrated to exhibit an improved antifibrotic effect on the treatment of CCL4-induced liver fibrosis by significantly increasing the level of matrix metalloproteinase 9 (MMP-9). In this study, we aimed to validate the therapeutic effect of BM45 on t...

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Bibliographic Details
Main Authors: Xing Lu, Ming Jiang, Juan Tian, Wei Liu, Fan Wu, Lijuan Yu, Guohui Feng, Shan Zhong, Ying Xiang, Hua Wen
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
liver cirrhosis
growth arrest-specific transcript 5
bone marrow (BM)-derived CD45 cells
hepatic stellate cells
MMP-9
p27
Online Access:http://www.sciencedirect.com/science/article/pii/S216225312030336X

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http://www.sciencedirect.com/science/article/pii/S216225312030336X

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