The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia

The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia

The Rho/Rho-kinase signaling pathway plays an important role in cerebral ischemia/reperfusion injury. However, very few studies have examined in detail the changes in the Rho/Rho-kinase signaling pathway in chronic cerebral ischemia. In this study, rat models of chronic cerebral ischemia were establ...

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Bibliographic Details
Main Authors: Ya-yun Yan, Xiao-ming Wang, Yan Jiang, Han Chen, Jin-ting He, Jing Mang, Yan-kun Shao, Zhong-xin Xu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; chronic cerebral ischemia; fasudil; Rho-kinase; alpha smooth muscle actin; myosin-binding subunit; cognitive impairment; caspase-3; apoptosis; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=9;spage=1441;epage=1449;aulast=Yan

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=9;spage=1441;epage=1449;aulast=Yan

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