Safety of Eplerenone for Kidney-Transplant Recipients with Impaired Renal Function and Receiving Cyclosporine A.

Safety of Eplerenone for Kidney-Transplant Recipients with Impaired Renal Function and Receiving Cyclosporine A.

Animal studies have highlighted the role of vascular mineralocorticoid receptor during Cyclosporine A-induced nephrotoxicity. Mineralocorticoid receptor antagonists could improve kidney survival but are not commonly used during renal impairment and in association with several immunosuppressive drugs...

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Bibliographic Details
Main Authors: Jean-Philippe Bertocchio, Coralie Barbe, Sylvie Lavaud, Olivier Toupance, Pierre Nazeyrollas, Frederic Jaisser, Philippe Rieu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4835088?pdf=render

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http://europepmc.org/articles/PMC4835088?pdf=render

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