Physiological functions and pathogenic potential of uric acid: A review

Uric acid is synthesized mainly in the liver, intestines and the vascular endothelium as the end product of an exogenous pool of purines, and endogenously from damaged, dying and dead cells, whereby nucleic acids, adenine and guanine, are degraded into uric acid. Mentioning uric acid generates dread...

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Bibliographic Details
Main Authors: Rashika El Ridi, Hatem Tallima
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Advanced Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123217300346