Rationale and Design of the Genetic Contribution to Drug Induced Renal Injury (DIRECT) Study

Rationale and Design of the Genetic Contribution to Drug Induced Renal Injury (DIRECT) Study

Nephrotoxicity from drugs accounts for 18% to 27% of cases of acute kidney injury. Determining a genetic predisposition may potentially be important in minimizing risk. The aims of this study are as follows: to determine whether a genetic predisposition exists for the development of drug-induced kid...

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Bibliographic Details
Main Authors: Linda Awdishu, Caroline M. Nievergelt, Andrew Davenport, Patrick T. Murray, Etienne Macedo, Jorge Cerda, Raj Chakaravarthi, Satish P. Ramachandra Rao, Arthur Holden, Stuart L. Goldstein, Ravindra L Mehta
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Kidney International Reports
Subjects:
AKI
antimicrobials
calcineurin inhibitors
nephrotoxicity
NSAIDs
pharmacogenomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024916300626

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http://www.sciencedirect.com/science/article/pii/S2468024916300626

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