Functional Status of Neuronal Calcium Sensor-1 Is Modulated by Zinc Binding

Functional Status of Neuronal Calcium Sensor-1 Is Modulated by Zinc Binding

Neuronal calcium sensor-1 (NCS-1) protein is abundantly expressed in the central nervous system and retinal neurons, where it regulates many vital processes such as synaptic transmission. It coordinates three calcium ions by EF-hands 2-4, thereby transducing Ca2+ signals to a wide range of protein t...

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Bibliographic Details
Main Authors: Philipp O. Tsvetkov, Andrei Yu. Roman, Viktoriia E. Baksheeva, Aliya A. Nazipova, Marina P. Shevelyova, Vasiliy I. Vladimirov, Michelle F. Buyanova, Dmitry V. Zinchenko, Andrey A. Zamyatnin, François Devred, Andrey V. Golovin, Sergei E. Permyakov, Evgeni Yu. Zernii
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
neuronal calcium sensor-1
zinc
calcium
magnesium
EF-hand motif
dopamine receptor D2R
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00459/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00459/full

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