Negative Regulation of Serine Threonine Kinase 11 (STK11) through miR-100 in Head and Neck Cancer

Negative Regulation of Serine Threonine Kinase 11 (STK11) through miR-100 in Head and Neck Cancer

Background: Serine Threonine Kinase 11 (STK11), also known as LKB1, is a tumor suppressor gene that regulates several biological processes such as apoptosis, energetic metabolism, proliferation, invasion, and migration. During malignant progression, different types of cancer inhibit STK11 function b...

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Bibliographic Details
Main Authors: Gabriela Figueroa-González, José F. Carrillo-Hernández, Itzel Perez-Rodriguez, David Cantú de León, Alma D. Campos-Parra, Antonio D. Martínez-Gutiérrez, Jossimar Coronel-Hernández, Verónica García-Castillo, César López-Camarillo, Oscar Peralta-Zaragoza, Nadia J. Jacobo-Herrera, Mariano Guardado-Estrada, Carlos Pérez-Plasencia
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
microRNA
mir-100
<i>STK11</i>
promoter methylation
head and neck cancer
Online Access:https://www.mdpi.com/2073-4425/11/9/1058

Internet

https://www.mdpi.com/2073-4425/11/9/1058

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